Luke Whitesell

The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3

Craig L. Bennett, Jacinda R. Christie, Fred Ramsdell et al. · Nature Genetics · 2001 · 3.4K citations

Life Sciences, Genetics, Immunology +13

Inhibition of heat shock protein HSP90-pp60v-src heteroprotein complex formation by benzoquinone ansamycins: essential role for stress proteins in oncogenic transformation.

Luke Whitesell, Edward G. Mimnaugh, B. de Costa et al. · Proceedings of the National Academy of Sciences · 1994 · 1.4K citations

Life Sciences, Molecular Biology, Pharmacology +14

Heat Shock Factor 1 Is a Powerful Multifaceted Modifier of Carcinogenesis

Chengkai Dai, Luke Whitesell, Arlin B. Rogers et al. · Cell · 2007 · 839 citations · Full text

Medicine, Cancer Biology, Molecular Biology +14

HSF1 Drives a Transcriptional Program Distinct from Heat Shock to Support Highly Malignant Human Cancers

Marc L. Mendillo, Sandro Santagata, Martina Koeva et al. · Cell · 2012 · 728 citations · Full text

Medicine, Cancer Biology, Molecular Biology +16

Widespread Macromolecular Interaction Perturbations in Human Genetic Disorders

Nidhi Sahni, S. Stephen Yi, Mikko Taipale et al. · Cell · 2015 · 643 citations · Full text

Life Sciences, Genetics, Molecular Genetics +14