Concepedia

Genotoxicity of a thiosulfonate compound derived from Allium sp. intended to be used in active food packaging: In vivo comet assay and micronucleus test

Pilar Mellado-García, María Puerto, Ana I. Prieto, Silvia Pichardo, Ana Martín-Cameán, Rosario Moyano, Alfonso Blanco, Ana M. Cameán

Mutation Research/Genetic Toxicology and Environmental Mutagenesis · 2016 · 30 citations · 39 references

Concepts

PharmacyChemistryToxicologyFood ToxicologyComet AssayEnvironmental GenotoxicantsGenotoxicity AssessmentGenotoxicity TestingMutagenicity AssessmentActive Edible PackagingComet Assay ScoringComet Assay ValidationGenotoxicityMicronucleus Frequency AnalysisMicronucleus Scoring CriteriaThiosulfate Chemistry

References

39

Directive 2010/63/EU of the European Parliament and Council of 22 September on the protection of animals used for scientific purposes

Eu · 2010 · 1.3K citations

Humanities, Animal Sciences, Animal Welfare +9

Biological properties of onions and garlic

Nieves Corzo, Mar Villamiel · Trends in Food Science & Technology · 2007 · 810 citations

Agriculture, Botany, Food Science +12

The comet assay: what can it really tell us?

Andrew Collins, Victoria L. Dobson, Mária Dušinská et al. · Mutation research. Fundamental and molecular mechanisms of mutagenesis · 1997 · 669 citations

Pharmacy, Molecular Biology, Good Laboratory Practice +6

Scientific opinion on genotoxicity testing strategies applicable to food and feed safety assessment

EFSA Journal · 2011 · 470 citations · Full text

Pharmacy, Food Science, Toxicology +13

How to reduce false positive results when undertaking in vitro genotoxicity testing and thus avoid unnecessary follow-up animal tests: Report of an ECVAM Workshop

David Kirkland, Stefan Pfuhler, David Tweats et al. · Mutation Research/Genetic Toxicology and Environmental Mutagenesis · 2007 · 437 citations

Pharmacy, Toxicology, Good Laboratory Practice +12