David Kirkland

Evaluation of the ability of a battery of three in vitro genotoxicity tests to discriminate rodent carcinogens and non-carcinogens

David Kirkland, Marilyn J. Aardema, L.M. Henderson et al. · Mutation Research/Genetic Toxicology and Environmental Mutagenesis · 2005 · 752 citations

Pharmacy, Toxicology, Genetic Toxicology +9

How to reduce false positive results when undertaking in vitro genotoxicity testing and thus avoid unnecessary follow-up animal tests: Report of an ECVAM Workshop

David Kirkland, Stefan Pfuhler, David Tweats et al. · Mutation Research/Genetic Toxicology and Environmental Mutagenesis · 2007 · 437 citations

Pharmacy, Toxicology, Good Laboratory Practice +12

Evaluation of the ability of a battery of three in vitro genotoxicity tests to discriminate rodent carcinogens and non-carcinogens

David Kirkland, Günter Speit · Mutation Research/Genetic Toxicology and Environmental Mutagenesis · 2008 · 318 citations

Pharmacy, Toxicology, Genetic Toxicology +9

A core in vitro genotoxicity battery comprising the Ames test plus the in vitro micronucleus test is sufficient to detect rodent carcinogens and in vivo genotoxins

David Kirkland, Lesley Reeve, D. Gatehouse et al. · Mutation Research/Genetic Toxicology and Environmental Mutagenesis · 2011 · 232 citations

Pharmacy, Toxicology, Reproductive Toxicology +12

Reduction of misleading (“false”) positive results in mammalian cell genotoxicity assays. I. Choice of cell type

Paul Fowler, Katie Smith, Jamie Young et al. · Mutation Research/Genetic Toxicology and Environmental Mutagenesis · 2011 · 225 citations

Pharmacy, Cell Biology, Toxicology +14