Concepedia

Evaluation of the effects of chemically different linkers on hepatic accumulations, cell tropism and gene silencing ability of cholesterol-conjugated antisense oligonucleotides

Shunsuke Wada, Hidenori Yasuhara, Fumito Wada, Motoki Sawamura, Reiko Waki, Tsuyoshi Yamamoto, Mariko Harada‐Shiba, Satoshi Obika

Journal of Controlled Release · 2016 · 48 citations · 30 references

DOI

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30

Silencing of microRNAs in vivo with ‘antagomirs’

Jan Krützfeldt, Nikolaus Rajewsky, Ravi Braich et al. · Nature · 2005 · 3.9K citations

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Lipid-like materials for low-dose, in vivo gene silencing

Kevin T. Love, Kerry P. Mahon, Christopher G. Levins et al. · Proceedings of the National Academy of Sciences · 2010 · 952 citations · Full text

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The ups and downs of nucleic acid duplex stability: structure-stability studies on chemically-modified DNA:RNA duplexes

Sandra Freier · Nucleic Acids Research · 1997 · 678 citations · Full text

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Breaking down the barriers: siRNA delivery and endosome escape

Monika Dominska, Derek M. Dykxhoorn · Journal of Cell Science · 2010 · 621 citations

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Towards a therapy for Angelman syndrome by targeting a long non-coding RNA

Linyan Meng, Amanda J. Ward, Seung Chun et al. · Nature · 2014 · 509 citations · Full text

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