Seung Chun

Astrocytes as determinants of disease progression in inherited amyotrophic lateral sclerosis

Koji Yamanaka, Seung Chun, Séverine Boillée et al. · Nature Neuroscience · 2008 · 1.1K citations · Full text

Neurodegenerative Diseases, Amyotrophic Lateral Sclerosis, Disease Progression +8

Targeted degradation of sense and antisense <i>C9orf72</i> RNA foci as therapy for ALS and frontotemporal degeneration

Clotilde Lagier‐Tourenne, Michael W. Baughn, Frank Rigo et al. · Proceedings of the National Academy of Sciences · 2013 · 551 citations · Full text

Neurodegenerative Diseases, Amyotrophic Lateral Sclerosis, Sporadic Als +13

Gain of Toxicity from ALS/FTD-Linked Repeat Expansions in C9ORF72 Is Alleviated by Antisense Oligonucleotides Targeting GGGGCC-Containing RNAs

Jie Jiang, Qiang Zhu, Tania F. Gendron et al. · Neuron · 2016 · 530 citations · Full text

Natural Sciences, Als/ftd-linked Repeat Expansions, Molecular Biology +5

Towards a therapy for Angelman syndrome by targeting a long non-coding RNA

Linyan Meng, Amanda J. Ward, Seung Chun et al. · Nature · 2014 · 509 citations · Full text

Translational Medicine, Systems Biology, Gene Therapies +12

Pharmacology of a Central Nervous System Delivered 2′-O-Methoxyethyl–Modified Survival of Motor Neuron Splicing Oligonucleotide in Mice and Nonhuman Primates

Frank Rigo, Seung Chun, Daniel A. Norris et al. · Journal of Pharmacology and Experimental Therapeutics · 2014 · 269 citations · Full text