Silencing of microRNAs in vivo with ‘antagomirs’

Jan Krützfeldt, Nikolaus Rajewsky, Ravi Braich, +4

Nature

‘ Antagomirs ’ImmunologyMicrorna DetectionSmall RnaGene Expression +3

A pancreatic islet-specific microRNA regulates insulin secretion

Matthew N. Poy, Lena Eliasson, Jan Krützfeldt, +8

Nature

DiabetesMicrorna DetectionGene ExpressionMedicineCell Biology +2

Specificity, duplex degradation and subcellular localization of antagomirs

Jan Krützfeldt, Satoru Kuwajima, Ravi Braich, +5

Nucleic Acids Research

Reduced β-cell mass and altered glucose sensing impair insulin-secretory function in βIRKO mice

Kenichi Otani, Rohit Kulkarni, Aaron C. Baldwin, +5

American Journal of Physiology-Endocrinology and Metabolism

Tmem27: A cleaved and shed plasma membrane protein that stimulates pancreatic β cell proliferation

Satoru Kuwajima, Jan Krützfeldt, Markus Stoffel

Cell Metabolism

Developmental BiologySignal TransductionPlasma MembraneSignaling PathwayCellular Biochemistry +5

Structure-function relationships of HDL in diabetes and coronary heart disease

Mathias Cardner, Mustafa Yalçınkaya, Sandra Goetze, +22

JCI Insight

Metabolic SyndromeHealthy SubjectsBiochemistryCardiovascular DiseaseMedicine +11

Insulin signaling and action in cultured skeletal muscle cells from lean healthy humans with high and low insulin sensitivity.

Jan Krützfeldt, Christiana Kausch, A. Volk, +4

Diabetes

Muscle FunctionInsulin ReceptorCellular PhysiologyInsulin SignalingMetabolic Syndrome +16

MicroRNA-29a in Adult Muscle Stem Cells Controls Skeletal Muscle Regeneration During Injury and Exercise Downstream of Fibroblast Growth Factor-2

Artur Galimov, Troy L. Merry, Edlira Luca, +7

Stem Cells

Muscle FunctionEccentric ExerciseAdult Skeletal MuscleFibroblast Growth Factor-2Cellular Physiology +16

FGF-2–dependent signaling activated in aged human skeletal muscle promotes intramuscular adipogenesis

Sebastian Mathes, Alexandra Fahrner, Umesh Ghoshdastider, +4

Proceedings of the National Academy of Sciences

AgingMetabolic SyndromeSkeletal MuscleFibroblast Growth FactorMetabolic Signaling +14

Effects of Troglitazone on Cellular Differentiation, Insulin Signaling, and Glucose Metabolism in Cultured Human Skeletal Muscle Cells

Christiana Kausch, Jan Krützfeldt, Anja Witke, +7

Biochemical and Biophysical Research Communications

Glucose MetabolismSkeletal MuscleCell SignalingPhysiologyMetabolic Regulation +6