Fumito Wada

Amido-bridged nucleic acids with small hydrophobic residues enhance hepatic tropism of antisense oligonucleotides in vivo

Tsuyoshi Yamamoto, Aiko Yahara, Reiko Waki et al. · Organic & Biomolecular Chemistry · 2015 · 51 citations

Evaluation of the effects of chemically different linkers on hepatic accumulations, cell tropism and gene silencing ability of cholesterol-conjugated antisense oligonucleotides

Shunsuke Wada, Hidenori Yasuhara, Fumito Wada et al. · Journal of Controlled Release · 2016 · 48 citations

Cholesterol-conjugated Antisense Oligonucleotides, Oxysterol, Biochemistry +8

Serial incorporation of a monovalent GalNAc phosphoramidite unit into hepatocyte-targeting antisense oligonucleotides

Tsuyoshi Yamamoto, Motoki Sawamura, Fumito Wada et al. · Bioorganic & Medicinal Chemistry · 2015 · 47 citations

Hepatocyte-targeting Antisense Oligonucleotides, Bioorganic Chemistry, Biochemistry +7

Ca²⁺enrichment in culture medium potentiates effect of oligonucleotides

Shinichiro Hori, Tsuyoshi Yamamoto, Reiko Waki et al. · Nucleic Acids Research · 2015 · 40 citations · Full text

Antisense Oligonucleotides Targeting Y-Box Binding Protein-1 Inhibit Tumor Angiogenesis by Downregulating Bcl-xL-VEGFR2/-Tie Axes

Kiyoko Setoguchi, Lin Cui, Nobutaka Hachisuka et al. · Molecular Therapy — Nucleic Acids · 2017 · 40 citations · Full text