Concepedia

Efficient dual sgRNA-directed large gene deletion in rabbit with CRISPR/Cas9 system

Yuning Song, Lin Yuan, Yong Wang, Mao Chen, Jichao Deng, Qingyan Lv, Tingting Sui, Zhanjun Li, Liangxue Lai

Cellular and Molecular Life Sciences · 2016 · 100 citations · 28 references

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28

A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity

Martin Jínek, Krzysztof Chylinski, Ines Fonfara et al. · Science · 2012 · 17.3K citations · Full text

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One-Step Generation of Mice Carrying Mutations in Multiple Genes by CRISPR/Cas-Mediated Genome Engineering

Haoyi Wang, Hui Yang, Chikdu Shivalila et al. · Cell · 2013 · 3.6K citations · Full text

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Cas9–crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria

Giedrius Gasiūnas, Rodolphe Barrangou, Philippe Horvath et al. · Proceedings of the National Academy of Sciences · 2012 · 2.8K citations · Full text

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DNA interrogation by the CRISPR RNA-guided endonuclease Cas9

Samuel H. Sternberg, Sy Redding, Martin Jínek et al. · Nature · 2014 · 1.9K citations · Full text

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Analysis of off-target effects of CRISPR/Cas-derived RNA-guided endonucleases and nickases

Seung Woo Cho, Sojung Kim, Yongsub Kim et al. · Genome Research · 2013 · 1.4K citations · Full text

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