Aurora kinase targeting in lung cancer reduces KRAS-induced transformation

Cancer statistics, 2015

Rebecca L. Siegel, Kimberly D. Miller, Ahmedin Jemal · CA A Cancer Journal for Clinicians · 2015 · 11.9K citations · Full text

Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours

Thomas G. Graeber, Cynthia Osmanian, Tyler Jacks et al. · Nature · 1996 · 2.3K citations

Tumor Biology, Hypoxia-mediated Selection, Redox Regulator +11

Tumour amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation

Hongyi Zhou, Jian Kuang, Ling Zhong et al. · Nature Genetics · 1998 · 1.3K citations

Tumor Biology, Signaling Pathway, Cell Regulation +9

VX-680, a potent and selective small-molecule inhibitor of the Aurora kinases, suppresses tumor growth in vivo

Elizabeth A. Harrington, David Bebbington, Jeffrey R. Moore et al. · Nature Medicine · 2004 · 948 citations · Full text

Selective Small-molecule Inhibitor, Signal Transduction, Signaling Pathway +11

Structural Basis of Aurora-A Activation by TPX2 at the Mitotic Spindle

Richard Bayliss, Teresa Sardón, Isabelle Vernos et al. · Molecular Cell · 2003 · 638 citations · Full text

Spin Dynamic, Spin Phenomenon, Natural Sciences +10