Single-Cell Transcriptomics of Human and Mouse Lung Cancers Reveals Conserved Myeloid Populations across Individuals and Species

Rapolas Žilionis, Camilla Engblom, Christina Pfirschke, +15

Immunity

Tumor BiologyOncologyTumor HeterogeneityMedicineSingle Cell Sequencing +10

Enhancement of Hematopoietic Stem Cell Repopulating Capacity and Self-Renewal in the Absence of the Transcription Factor C/EBPα

Pu Zhang, Junko Iwasaki-Arai, Hiromi Iwasaki, +9

Immunity

Transcription Factor C/ebpαDevelopmental BiologyMedicineStem Cell MobilizationHematology +6

Requirement of the NF-κB Subunit p65/RelA for K-Ras–Induced Lung Tumorigenesis

Daniela S. Daniela Sanchez Bassères, Aaron Ebbs, Elena Levantini, +1

Cancer Research

Lung InflammationImmunologyCell DeathCancer BiologyK-ras-induced Lung Cancer +14

Fatty acid synthase mediates EGFR palmitoylation in EGFR mutated non‐small cell lung cancer

Azhar Ali, Elena Levantini, Jun Ting Teo, +12

EMBO Molecular Medicine

Cabozantinib Eradicates Advanced Murine Prostate Cancer by Activating Antitumor Innate Immunity

Akash Patnaik, Kenneth D. Swanson, Eva Csizmadia, +26

Cancer Discovery

C/EBPa controls acquisition and maintenance of adult haematopoietic stem cell quiescence

Min Ye, Hong Zhang, Giovanni Amabile, +8

Nature Cell Biology

Treatment of Chronic Myelogenous Leukemia by Blocking Cytokine Alterations Found in Normal Stem and Progenitor Cells

Robert S. Welner, Giovanni Amabile, Deepak Bararia, +9

Cancer Cell

Progenitor CellsHematological MalignancyMedicineMixed-phenotype Acute LeukemiaMalignant Blood Disorder +12

Identification of a myeloid committed progenitor as the cancer-initiating cell in acute promyelocytic leukemia

Florence C. Guibal, Meritxell Alberich-Jordà, Hideyo Hirai, +9

Blood

Sox4 Is a Key Oncogenic Target in C/EBPα Mutant Acute Myeloid Leukemia

Hong Zhang, Meritxell Alberich-Jordà, Giovanni Amabile, +18

Cancer Cell

Hematological MalignancyMedicineHematologyCancer GeneticsSystems Biology +5

Hematopoietic Differentiation Is Required for Initiation of Acute Myeloid Leukemia

Min Ye, Hong Zhang, Henry Yang, +10

Cell stem cell

Hematological MalignancyDevelopmental BiologyMixed-phenotype Acute LeukemiaAcute Myeloid LeukemiaHematology +4