David Bebbington

VX-680, a potent and selective small-molecule inhibitor of the Aurora kinases, suppresses tumor growth in vivo

Elizabeth A. Harrington, David Bebbington, Jeffrey R. Moore et al. · Nature Medicine · 2004 · 948 citations · Full text

Selective Small-molecule Inhibitor, Signal Transduction, Signaling Pathway +11

The discovery of the potent aurora inhibitor MK-0457 (VX-680)

David Bebbington, Hayley Binch, Jean‐Damien Charrier et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 99 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Medicine +8

Antagonists of the human adenosine A2A receptor. Part 1: Discovery and synthesis of thieno[3,2-d]pyrimidine-4-methanone derivatives

Roger J. Gillespie, David R. Adams, David Bebbington et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 48 citations · Full text

Molecular Pharmacology, Biochemistry, Functional Selectivity +6

Indoline derivatives as 5-HT 2C receptor agonists

Jonathan Bentley, David R. Adams, David Bebbington et al. · Bioorganic & Medicinal Chemistry Letters · 2004 · 44 citations · Full text

Functional Selectivity, Medicine, Physiology +5

Asymmetric total synthesis of the individual diastereoisomers of hypoglycin A.

Jack E. Baldwin, Robert M. Adlington, David Bebbington et al. · Tetrahedron · 1994 · 39 citations

Medicinal Chemistry, Biosynthesis, Bioorganic Chemistry +11