Concepedia

Selective Killing of Cancer Cells Based on Loss of Heterozygosity and Normal Variation in the Human Genome: A New Paradigm for Anticancer Drug Therapy

James P. Basilion, Andrea R. Schievella, Erica Burns, Patrice Rioux, Jeffrey Olson, Brett P. Monia, Kristina M. Lemonidis, Vincent P. Stanton, David E. Housman

Molecular Pharmacology · 1999 · 35 citations · 33 references

DOI

Concepts

References

33

An Adenovirus Mutant That Replicates Selectively in p53- Deficient Human Tumor Cells

James R. Bischoff, David H. Kirn, Angelica Williams et al. · Science · 1996 · 1.8K citations

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ONYX-015, an E1B gene-attenuated adenovirus, causes tumor-specific cytolysis and antitumoral efficacy that can be augmented by standard chemotherapeutic agents

Carla Heise, Adam Sampson-Johannes, Angelica Williams et al. · Nature Medicine · 1997 · 947 citations

, , +13

Evaluation of 2‘-modified oligonucleotides containing 2‘-deoxy gaps as antisense inhibitors of gene expression

Brett P. Monia, Elena A. Lesnik, C. Gonzalez et al. · Journal of Biological Chemistry · 1993 · 770 citations · Full text

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Cationic lipids enhance cellular uptake and activity of phosphorothioate antisense oligonucleotides.

C. Frank Bennett, M Y Chiang, Huai En Huang Chan et al. · Molecular Pharmacology · 1992 · 616 citations

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Purification and characterization of replication protein A, a cellular protein required for in vitro replication of simian virus 40 DNA.

Marc S. Wold, Thomas J. Kelly · Proceedings of the National Academy of Sciences · 1988 · 498 citations

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