Concepedia

Essential Gene Function

Essential Gene Function is a fundamental biological process or activity, within the category of gene functions, that is indispensable for the survival, growth, or reproduction of an organism under standard physiological conditions.

1.1K

Publications

103.2K

Citations

5.6K

Authors

1.3K

Institutions

Publications per year

2017–2026

190

Parents

Publications

1.1K

Insulin Resistance and a Diabetes Mellitus-Like Syndrome in Mice Lacking the Protein Kinase Akt2 (PKBβ)

Han Cho, James Mu, Jason K. Kim et al. · Science · 2001 · 1.8K citations

, , +17

A global genetic interaction network maps a wiring diagram of cellular function

Michael Costanzo, Benjamin VanderSluis, Elizabeth N. Koch et al. · Science · 2016 · 1.4K citations · Full text

, , +15

Essential function for the kinase TAK1 in innate and adaptive immune responses

Shintaro Sato, Hideki Sanjo, Kiyoshi Takeda et al. · Nature Immunology · 2005 · 968 citations

, , +16

An essential function for the nuclear receptor RORγt in the generation of fetal lymphoid tissue inducer cells

Gérard Eberl, Shana Marmon, Mary Jean Sunshine et al. · Nature Immunology · 2003 · 964 citations · Full text

, , +16

Phosphatidylinositol 3-Kinase Encoded by Yeast <i>VPS</i> 34 Gene Essential for Protein Sorting

Peter Schu, Kaoru Takegawa, Michael Fry et al. · Science · 1993 · 921 citations

, , +15

1–5 of 1.1K

Authors

5.6K

  1. CB
    Charles Boone

    University of Toronto, Canada

    9 publications · 2.6K citations

    9

    h-index

  2. JL
    Joe Lutkenhaus

    University of Kansas Medical Center, United States

    8 publications · 1K citations

    8

    h-index

  3. MC
    Marian Carlson

    Columbia University, United States

    7 publications · 519 citations

    7

    h-index

  4. FW
    Fred Winston

    Harvard University, United States

    7 publications · 767 citations

    7

    h-index

  5. BA
    Brenda Andrews

    University of Toronto, Canada

    7 publications · 2.1K citations

    7

    h-index

1–5 of 5.6K

Institutions

1.3K

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    36 h-index

    132 publications

    36.4K citations

  2. Harvard University

    Cambridge, United States

    31 h-index

    110 publications

    13.1K citations

  3. Centre National de la Recherche Scientifique

    Paris, France

    30 h-index

    196 publications

    18.2K citations

  4. Stanford University

    Stanford, United States

    25 h-index

    65 publications

    8K citations

  5. Massachusetts Institute of Technology

    Cambridge, United States

    22 h-index

    80 publications

    17.8K citations

  6. University of Wisconsin–Madison

    Madison, United States

    20 h-index

    80 publications

    8.7K citations

  7. The University of Tokyo

    Tokyo, Japan

    19 h-index

    86 publications

    13.1K citations

  8. University of Toronto

    Toronto, Canada

    19 h-index

    138 publications

    58.2K citations

1–8 of 1.3K

Venues

  1. Molecular and Cellular Biology

    MCB · 101 publications · 10K citations

    59

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 74 publications · 10.1K citations

    52

    h-index

  3. Journal of Bacteriology

    JB · 85 publications · 6.8K citations

    51

    h-index

  4. Genetics

    63 publications · 4.4K citations

    38

    h-index

  5. Journal of Biological Chemistry

    JBC · 44 publications · 3.8K citations

    33

    h-index

1–5