Insulin Resistance and a Diabetes Mellitus-Like Syndrome in Mice Lacking the Protein Kinase Akt2 (PKBβ)

Han Cho, James Mu, Jason K. Kim, +7

Science

Metabolic DisorderHomeostatic MechanismGlucose HomeostasisInsulin SignalingMetabolic Syndrome +18

Regulation of circadian behaviour and metabolism by REV-ERB-α and REV-ERB-β

Han Cho, Xuan Zhao, Megumi Hatori, +12

Nature

Energy HomeostasisSystems BiologySignal TransductionMedicinePhysiology +10

Akt1/PKBα Is Required for Normal Growth but Dispensable for Maintenance of Glucose Homeostasis in Mice

Han Cho, Joanne L. Thorvaldsen, Qingwei Chu, +2

Journal of Biological Chemistry

Role for Akt3/Protein Kinase Bγ in Attainment of Normal Brain Size

Rachael Easton, Han Cho, Kristin Roovers, +10

Molecular and Cellular Biology

Brain DevelopmentBrain ScienceMetabolic RemodelingNormal Organ SizeSynaptic Signaling +23

Rev-Erbs repress macrophage gene expression by inhibiting enhancer-directed transcription

Michael T. Lam, Han Cho, Hanna P. Lesch, +13

Nature

Enhancer-directed TranscriptionTranscriptional RegulationCell RegulationGene RegulationGene Expression +4

Isoform-specific Regulation of Insulin-dependent Glucose Uptake by Akt/Protein Kinase B

Sun Sik Bae, Han Cho, James Mu, +1

Journal of Biological Chemistry

Metabolic RemodelingInsulin-dependent Glucose UptakeCellular PhysiologyInsulin SignalingMetabolic Syndrome +18

Akt1 Regulates a JNK Scaffold during Excitotoxic Apoptosis

Albert H. Kim, Hiroko Yano, Han Cho, +5

Neuron

Signal TransductionSignaling PathwayApoptosisCell DeathTumor Suppressor +4

Circadian Amplitude Regulation via FBXW7-Targeted REV-ERBα Degradation

Xuan Zhao, Tsuyoshi Hirota, Xuemei Han, +12

Cell

Signal TransductionMedicinePhysiologyCircadian Amplitude RegulationEndocrinology +4

Circadian clock cryptochrome proteins regulate autoimmunity

Qi Cao, Xuan Zhao, Jing‐Wen Bai, +23

Proceedings of the National Academy of Sciences

Isoform-specific requirement for Akt1 in the developmental regulation of cellular metabolism during lactation

Robert Boxer, Douglas B. Stairs, Katherine D. Dugan, +9

Cell Metabolism

Cellular PhysiologyHuman LactationLactationIsoform-specific RequirementCellular Metabolism +15