IL-22–producing “T22” T cells account for upregulated IL-22 in atopic dermatitis despite reduced IL-17–producing TH17 T cells

Interleukin (IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides

Spencer C. Liang, Xiangyang Tan, Deborah Luxenberg et al. · The Journal of Experimental Medicine · 2006 · 2.3K citations · Full text

Life Sciences, Immunology, Microbiology +17

Interleukin-22, a TH17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis

Yan Zheng, Dimitry M. Danilenko, Patricia Valdez et al. · Nature · 2006 · 1.8K citations

Life Sciences, Immunology, Pathology +14

Cytokine modulation of atopic dermatitis filaggrin skin expression

Michael Howell, Byung Eui Kim, Peisong Gao et al. · Journal of Allergy and Clinical Immunology · 2007 · 1.1K citations · Full text

Medicine, Dermatology, Immunology +14

Psoriasis Vulgaris Lesions Contain Discrete Populations of Th1 and Th17 T Cells

Michelle A. Lowes, Toyoko Kikuchi, Judilyn Fuentes‐Duculan et al. · Journal of Investigative Dermatology · 2008 · 1.1K citations · Full text

Life Sciences, Dermatology, Immunology +12

IL-22 Inhibits Epidermal Differentiation and Induces Proinflammatory Gene Expression and Migration of Human Keratinocytes

Katia Boniface, François‐Xavier Bernard, Martine Garcia et al. · The Journal of Immunology · 2005 · 841 citations · Full text

Life Sciences, Dermatology, Immunology +17