Toyoko Kikuchi

Psoriasis Vulgaris Lesions Contain Discrete Populations of Th1 and Th17 T Cells

Michelle A. Lowes, Toyoko Kikuchi, Judilyn Fuentes‐Duculan et al. · Journal of Investigative Dermatology · 2008 · 1.1K citations

Th17 T Cells, Autoimmune Disease, Medicine +8

IL-22–producing “T22” T cells account for upregulated IL-22 in atopic dermatitis despite reduced IL-17–producing TH17 T cells

Kristine Nograles, Lisa C. Zaba, Avner Shemer et al. · Journal of Allergy and Clinical Immunology · 2009 · 606 citations · Full text

Inflammation, Atopic Dermatitis, Upregulated Il-22 +6

The Majority of Epidermal T Cells in Psoriasis Vulgaris Lesions can Produce Type 1 Cytokines, Interferon-γ, Interleukin-2, and Tumor Necrosis Factor-α, Defining TC1 (Cytotoxic T Lymphocyte) and TH1 Effector Populations:1 a Type 1 Differentiation Bias is also Measured in Circulating Blood T Cells in Psoriatic Patients

Lisa M. Austin, Maki Ozawa, Toyoko Kikuchi et al. · Journal of Investigative Dermatology · 1999 · 482 citations · Full text

Immunodeficiencies, Immunology, Immune Regulation +16

Increase in TNF-α and inducible nitric oxide synthase-expressing dendritic cells in psoriasis and reduction with efalizumab (anti-CD11a)

Michelle A. Lowes, Francesca Chamian, Maria Veronica Abello et al. · Proceedings of the National Academy of Sciences · 2005 · 448 citations · Full text

Nitric Oxide, Immune Regulation, Immunology +18

Blockade of T Lymphocyte Costimulation with Cytotoxic T Lymphocyte–Associated Antigen 4–Immunoglobulin (Ctla4ig) Reverses the Cellular Pathology of Psoriatic Plaques, Including the Activation of Keratinocytes, Dendritic Cells, and Endothelial Cells

Judith R. Abrams, Susan L. Kelley, Elizabeth Hayes et al. · The Journal of Experimental Medicine · 2000 · 319 citations · Full text

Endothelial Cells, Immunodeficiencies, Immunology +22