Concepedia

Anxiolytic-Like Effects of the Corticotropin-Releasing Factor1 (CRF1) Antagonist DMP904 [4-(3-pentylamino)-2,7-dimethyl-8-(2-methyl-4-methoxyphenyl)-pyrazolo-[1,5-a]-pyrimidine] Administered Acutely or Chronically at Doses Occupying Central CRF1 Receptors in Rats

Snježana Lelas, Harvey Wong, Yu-Wen Li, Karen Heman, Kim Zeller, Kristine K Sieracki, Joseph Polino, Helen E. Godonis, Shelly X. Ren, Xiao‐Xin Yan,

Journal of Pharmacology and Experimental Therapeutics · 2004 · 55 citations · 18 references

DOI

Concepts

References

18

Effects of the high-affinity corticotropin-releasing hormone receptor 1 antagonist R121919 in major depression: the first 20 patients treated

Astrid Zobel, Thomas Nickel, Heike Künzel et al. · Journal of Psychiatric Research · 2000 · 704 citations

, , +14

Oral administration of a corticotropin-releasing hormone receptor antagonist significantly attenuates behavioral, neuroendocrine, and autonomic responses to stress in primates

Kamal E. Habib, Katherine P Weld, Kenner C. Rice et al. · Proceedings of the National Academy of Sciences · 2000 · 402 citations

, , +17

4-(2-Chloro-4-methoxy-5-methylphenyl)-N-[(1 S)-2-cyclopropyl-1-(3-fluoro-4-methylphenyl)ethyl]5-methyl-N-(2-propynyl)-1, 3-thiazol-2-amine Hydrochloride (SSR125543A), a Potent and Selective Corticotrophin-Releasing Factor1 Receptor Antagonist. II. Characterization in Rodent Models of Stress-Related Disorders

Guy Griebel, Jacques Simiand, R. Steinberg et al. · Journal of Pharmacology and Experimental Therapeutics · 2002 · 236 citations

, , +17

Characterization of the behavioral profile of the non-peptide CRF receptor antagonist CP-154,526 in anxiety models in rodents

Ghislaine Perrault, Guy Griebel, D. J. Sanger · Psychopharmacology · 1998 · 205 citations

, , +12

Brain Penetrance, Receptor Occupancy and Antistress In Vivo Efficacy of a Small Molecule Corticotropin Releasing Factor Type I Receptor Selective Antagonist

Stephen C. Heinrichs · Neuropsychopharmacology · 2002 · 148 citations · Full text

, , +11