Jacques Simiand

Benzodiazepine impairs and β-carboline enhances performance in learning and memory tasks

Patrice Venault, Georges Chapouthier, Lia Prado de Carvalho et al. · Nature · 1986 · 504 citations

Medicine, Neuroscience, Pharmacology +8

Anxiolytic- and antidepressant-like effects of the non-peptide vasopressin V _1b receptor antagonist, SSR149415, suggest an innovative approach for the treatment of stress-related disorders

Guy Griebel, Jacques Simiand, Claudine Serradeil‐Le Gal et al. · Proceedings of the National Academy of Sciences · 2002 · 462 citations · Full text

Medicine, Neuroscience, Pharmacology +17

SR 141716, a CB1 cannabinoid receptor antagonist, selectively reduces sweet food intake in marmoset.

Jacques Simiand, Madeline Keane, Keane Pe et al. · PubMed · 1998 · 267 citations

Medicine, Pharmacology, Human Nutrition +11

4-(2-Chloro-4-methoxy-5-methylphenyl)-N-[(1 S)-2-cyclopropyl-1-(3-fluoro-4-methylphenyl)ethyl]5-methyl-N-(2-propynyl)-1, 3-thiazol-2-amine Hydrochloride (SSR125543A), a Potent and Selective Corticotrophin-Releasing Factor1 Receptor Antagonist. II. Characterization in Rodent Models of Stress-Related Disorders

Guy Griebel, Jacques Simiand, R. Steinberg et al. · Journal of Pharmacology and Experimental Therapeutics · 2002 · 236 citations

Medicine, Neuroscience, Pharmacology +17

Characterization of (2 S,4 R)-1-[5-Chloro-1-[(2,4-dimethoxyphenyl)sulfonyl]-3-(2-methoxy-phenyl)-2-oxo-2,3-dihydro-1 H-indol-3-yl]-4-hydroxy-N,N-dimethyl-2-pyrrolidine carboxamide (SSR149415), a Selective and Orally Active Vasopressin V1b Receptor Antagonist

Claudine Serradeil‐Le Gal, Jean Wagnon, Jacques Simiand et al. · Journal of Pharmacology and Experimental Therapeutics · 2002 · 210 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +14