Anxiolytic- and antidepressant-like effects of the non-peptide vasopressin V _1b receptor antagonist, SSR149415, suggest an innovative approach for the treatment of stress-related disorders

Guy Griebel, Jacques Simiand, Claudine Serradeil‐Le Gal, +5

Proceedings of the National Academy of Sciences

Psychotropic MedicationAffective NeurosciencePsychopharmacologyPharmacotherapyInnovative Approach +22

Biochemical and pharmacological properties of SR 49059, a new, potent, nonpeptide antagonist of rat and human vasopressin V1a receptors.

C. Serradeil‐Le Gal, Jean Wagnon, Corinne Garcia, +7

Journal of Clinical Investigation

Avp V2ImmunologyPharmacotherapyExperimental PharmacologyInflammation +16

Characterization of (2 S,4 R)-1-[5-Chloro-1-[(2,4-dimethoxyphenyl)sulfonyl]-3-(2-methoxy-phenyl)-2-oxo-2,3-dihydro-1 H-indol-3-yl]-4-hydroxy-N,N-dimethyl-2-pyrrolidine carboxamide (SSR149415), a Selective and Orally Active Vasopressin V1b Receptor Antagonist

Claudine Serradeil‐Le Gal, Jean Wagnon, Jacques Simiand, +12

Journal of Pharmacology and Experimental Therapeutics

Unsymmetrical cyano-cuprates as reagents in substitution and addition reactions

Jean-Pierre Gorlier, Louis Hamon, J. Levisalles, +1

Journal of the Chemical Society Chemical Communications

Asymmetric CatalysisChemical EngineeringCross-coupling ReactionJ. LevisallesEngineering +11

[2.pi. + 6.pi.] Cycloaddition reactions between ligands coordinated to an iron atom

R. Davis, Tom A. Dodds, Tzong‐Hsiung Hseu, +5

Journal of the American Chemical Society

Inorganic ChemistryMolecular SciencesHeterocyclicBiochemistryDonut Icon +12

Biological characterization of rodent and human vasopressin V_1breceptors using SSR-149415, a nonpeptide V_1breceptor ligand

Claudine Serradeil‐Le Gal, Danièle Raufaste, Sylvain Derick, +6

American Journal of Physiology-Regulatory, Integrative and Comparative Physiology

Key Amino Acids Located within the Transmembrane Domains 5 and 7 Account for the Pharmacological Specificity of the Human V1b Vasopressin Receptor

Sylvain Derick, Ana Peña, Thierry Durroux, +5

Molecular Endocrinology

Cellular PhysiologyGastrointestinal Peptide HormonePharmacological SpecificityTransmembrane Domains 5-R Selectivity +16

Renin inhibitors. Free-Wilson and correlation analysis of the inhibitory potency of a series of pepstatin analogs on plasma renin

Dino Nisato, Jean Wagnon, Georges Callet, +6

Journal of Medicinal Chemistry

Inhibitory ActivityMedicinal ChemistryBiochemistryRenin InhibitorsMedicine +10

Effects of a renin inhibitor, SR 43845, and of captopril on blood pressure and plasma active renin in conscious sodium-replete macaca

C Lacour, Catherine Cazaubon, Alain Roccon, +3

Journal of Hypertension