Polymorphisms in FKBP5 are associated with increased recurrence of depressive episodes and rapid response to antidepressant treatment

Elisabeth B. Binder, Daria Salyakina, Peter Lichtner, +35

Nature Genetics

PsychopathologyPsychiatryMood SymptomGeneticsPsychiatric Genetics +11

Effects of the high-affinity corticotropin-releasing hormone receptor 1 antagonist R121919 in major depression: the first 20 patients treated

Astrid Zobel, Thomas Nickel, Heike Künzel, +3

Journal of Psychiatric Research

Stress HormonePsychiatryMood SymptomMedicineAntagonist R121919 +10

Cortisol response in the combined dexamethasone/CRH test as predictor of relapse in patients with remitted depression

Astrid Zobel, Thomas Nickel, Annette Sonntag, +2

Journal of Psychiatric Research

Remitted DepressionStress HormonePsychiatryMood SymptomCombined Dexamethasone/crh Test +8

Response and remission criteria in major depression – A validation of current practice

Michael Riedel, Hans‐Jürgen Möller, Michael Obermeier, +12

Journal of Psychiatric Research

PsychopathologyPsychiatryDepression TreatmentMedicineMood Symptom +12

Clinical characteristics and treatment outcome in a representative sample of depressed inpatients – Findings from the Munich Antidepressant Response Signature (MARS) project

Johannes M. Hennings, Toshimi Owashi, Elisabeth B. Binder, +17

Journal of Psychiatric Research

Treatment OutcomeRepresentative SamplePsychiatryMood SymptomClinical Characteristics +11

Clinical and Neurobiological Effects of Tianeptine and Paroxetine in Major Depression

Thomas Nickel, Annette Sonntag, Julia Schill, +8

Journal of Clinical Psychopharmacology

Neurobiological EffectsPsychotropic MedicationNeurotransmitterPsychopharmacologyPharmacotherapy +18

Pharmacological and Nonpharmacological Factors Influencing Hypothalamic–Pituitary–Adrenocortical Axis Reactivity in Acutely Depressed Psychiatric In-patients, Measured by the Dex-CRH Test

Heike Künzel, Elisabeth B. Binder, Thomas Nickel, +9

Neuropsychopharmacology

Psychiatric In-patientsStress HormonePsychiatryMedicineDex-crh Test +10

Treatment of depression with the CRH-1-receptor antagonist R121919: endocrine changes and side effects

Heike Künzel, Astrid Zobel, Thomas Nickel, +4

Journal of Psychiatric Research

Molecular PharmacologyEndocrine ChangesStress HormonePsychiatryMood Symptom +11

HPA-axis regulation at in-patient admission is associated with antidepressant therapy outcome in male but not in female depressed patients

Elisabeth B. Binder, Heike Künzel, Thomas Nickel, +5

Psychoneuroendocrinology

Antidepressant Therapy OutcomePsychiatryMood SymptomDepressionMood Spectrum +7

oxLDL uptake by dendritic cells induces upregulation of scavenger-receptors, maturation and differentiation

Thomas Nickel, Henner Hanssen, Zelka Sicic, +7

Atherosclerosis

Signal TransductionOxysterolCell SignalingCell TraffickingPhysiology +8