Joseph Polino

Anxiolytic-Like Effects of the Corticotropin-Releasing Factor1 (CRF1) Antagonist DMP904 [4-(3-pentylamino)-2,7-dimethyl-8-(2-methyl-4-methoxyphenyl)-pyrazolo-[1,5-a]-pyrimidine] Administered Acutely or Chronically at Doses Occupying Central CRF1 Receptors in Rats

Snježana Lelas, Harvey Wong, Yu-Wen Li et al. · Journal of Pharmacology and Experimental Therapeutics · 2004 · 55 citations

Medicine, Pharmacology, Pharmacotherapy +15

Negative Allosteric Modulators Selective for The NR2B Subtype of The NMDA Receptor Impair Cognition in Multiple Domains

Michael R. Weed, Mark Bookbinder, Joseph Polino et al. · Neuropsychopharmacology · 2015 · 25 citations · Full text

Life Sciences, Neuroscience, Pharmacology +17

Preclinical Characterization of (R)-3-((3S,4S)-3-fluoro-4-(4-hydroxyphenyl)piperidin-1-yl)-1-(4-methylbenzyl)pyrrolidin-2-one (BMS-986169), a Novel, Intravenous, Glutamate N-Methyl-D-Aspartate 2B Receptor Negative Allosteric Modulator with Potential in Major Depressive Disorder

Linda J. Bristow, Jyoti Gulia, Michael R. Weed et al. · Journal of Pharmacology and Experimental Therapeutics · 2017 · 17 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Nicotinic alpha 7 receptor agonists EVP-6124 and BMS-933043, attenuate scopolamine-induced deficits in visuo-spatial paired associates learning

Michael R. Weed, Joseph Polino, Laura J. Signor et al. · PLoS ONE · 2017 · 12 citations · Full text

Medicine, Neuroscience, Pharmacology +17

Discovery of (S,E)-3-(2-fluorophenyl)-N-(1-(3-(pyridin-3-yloxy)phenyl)ethyl)-acrylamide as a potent and efficacious KCNQ2 (Kv7.2) opener for the treatment of neuropathic pain

Yong‐Jin Wu, Charles M. Conway, Li‐Qiang Sun et al. · Bioorganic & Medicinal Chemistry Letters · 2013 · 11 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +9