Concepedia

Evaluation of 89 Compounds for Identification of Substrates for Cynomolgus Monkey CYP2C76, a New Bupropion/Nifedipine Oxidase

Shinya Hosaka, Norie Murayama, Masahiro Satsukawa, Makiko Shimizu, Shotaro Uehara, Hideki Fujino, Kazuhide Iwasaki, Shunsuke Iwano, Yasuhiro Uno, Hiroshi Yamazaki

Drug Metabolism and Disposition · 2014 · 24 citations · 23 references

DOI

Concepts

References

23

THE HUMAN INTESTINAL CYTOCHROME P450 “PIE”

Mary F. Paine, Heather L. Hart, Shana S. Ludington et al. · Drug Metabolism and Disposition · 2006 · 874 citations

, , +12

Structural basis for ligand promiscuity in cytochrome P450 3A4

M. Ekroos, Tove Sjögren · Proceedings of the National Academy of Sciences · 2006 · 756 citations · Full text

, , +17

Characterization of rat and human liver microsomal cytochrome P-450 forms involved in nifedipine oxidation, a prototype for genetic polymorphism in oxidative drug metabolism.

F. Peter Guengerich, M V Martin, Philippe Beaune et al. · Journal of Biological Chemistry · 1986 · 730 citations · Full text

, , +17

The Structure of Human Cytochrome P450 2C9 Complexed with Flurbiprofen at 2.0-Å Resolution

Michael R. Wester, Jason K. Yano, G. Schoch et al. · Journal of Biological Chemistry · 2004 · 439 citations · Full text

, , +17

CYP2B6 Mediates the In Vitro Hydroxylation of Bupropion: Potential Drug Interactions with Other Antidepressants

L M Hesse, Karthik Venkatakrishnan, Michael H. Court et al. · Drug Metabolism and Disposition · 2000 · 399 citations

, , +17