Shunsuke Iwano

Decreased coumarin 7-hydroxylase activities and CYP2A6 expression levels in humans caused by genetic polymorphism in CYP2A6 promoter region (CYP2A6*9)

Kazuma Kiyotani, Hiroshi Yamazaki, Masaki Fujieda et al. · Pharmacogenetics · 2003 · 71 citations

Medicine, Genetics, Pharmacology +12

Ethnic differences between Japanese and Caucasians in the expression levels of mRNAs for CYP3A4, CYP3A5 and CYP3A7: lack of co-regulation of the expression of CYP3A in Japanese livers

Satoshi Yamaori, Hiroshi Yamazaki, Shunsuke Iwano et al. · Xenobiotica · 2005 · 55 citations

Life Sciences, Molecular Biology, Pharmacology +12

CYP3A5 Contributes Significantly to CYP3A-mediated Drug Oxidations in Liver Microsomes from Japanese Subjects

Satoshi Yamaori, Hiroshi Yamazaki, Shunsuke Iwano et al. · Drug Metabolism and Pharmacokinetics · 2004 · 52 citations

Medicine, Pharmacology, Toxicology +13

Lung tumorigenesis promoted by anti-apoptotic effects of cotinine, a nicotine metabolite through activation of PI3K/Akt pathway

Tomohisa Nakada, Kazuma Kiyotani, Shunsuke Iwano et al. · The Journal of Toxicological Sciences · 2012 · 51 citations · Full text

Medicine, Oncology, Pharmacology +15

Aryl hydrocarbon hydroxylase represents CYP1B1, and not CYP1A1, in human freshly isolated white cells: trimodal distribution of Japanese population according to induction of CYP1B1 mRNA by environmental dioxins.

Kenji Toide, Hiroshi Yamazaki, Rikako Nagashima et al. · PubMed · 2003 · 39 citations

Medicine, Molecular Biology, Toxicology +11