Concepedia

THE HUMAN INTESTINAL CYTOCHROME P450 “PIE”

Mary F. Paine, Heather L. Hart, Shana S. Ludington, Robert L. Haining, Allan E. Rettie, Darryl C. Zeldin

Drug Metabolism and Disposition · 2006 · 874 citations · 33 references

DOI

Concepts

References

33

The Carbon Monoxide-binding Pigment of Liver Microsomes

Tsuneo Omura, Ryo Sato · Journal of Biological Chemistry · 1964 · 11.8K citations · Full text

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Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians.

Tsutomu Shimada, Hiroshi Yamazaki, Mayumi Mimura et al. · Journal of Pharmacology and Experimental Therapeutics · 1994 · 2.8K citations

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Characterization of Interintestinal and Intraintestinal Variations in Human CYP3A-Dependent Metabolism

Mary F. Paine, Mehraneh Khalighi, Jeannine M. Fisher et al. · Journal of Pharmacology and Experimental Therapeutics · 1997 · 792 citations

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Cytochrome P 450 isoenzymes, epoxide hydrolase and glutathione transferases in rat and human hepatic and extrahepatic tissues.

Isabelle de Waziers, Paul‐Henri Cugnenc, Chunsong Yang et al. · Journal of Pharmacology and Experimental Therapeutics · 1990 · 502 citations

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Identification of glucocorticoid-inducible cytochromes P-450 in the intestinal mucosa of rats and man.

Paul B. Watkins, Steven Wrighton, Erin G. Schuetz et al. · Journal of Clinical Investigation · 1987 · 483 citations · Full text

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