Steven Wrighton

Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression

Peter Kuehl, Jiong Zhang, Yvonne Lin et al. · Nature Genetics · 2001 · 2.2K citations

Life Sciences, Genetics, Molecular Biology +17

THE CONDUCT OF IN VITRO AND IN VIVO DRUG-DRUG INTERACTION STUDIES: A PHARMACEUTICAL RESEARCH AND MANUFACTURERS OF AMERICA (PhRMA) PERSPECTIVE

Thorir D. Bjornsson, John T. Callaghan, Heidi J. Einolf et al. · Drug Metabolism and Disposition · 2003 · 784 citations

Medicine, Pharmacokinetics, Pharmacology +17

Intronic polymorphism in CYP3A4 affects hepatic expression and response to statin drugs

Daqing Wang, Yingying Guo, Steven Wrighton et al. · The Pharmacogenomics Journal · 2010 · 507 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +14

Identification of glucocorticoid-inducible cytochromes P-450 in the intestinal mucosa of rats and man.

Paul B. Watkins, Steven Wrighton, Erin G. Schuetz et al. · Journal of Clinical Investigation · 1987 · 483 citations · Full text

Medicine, Biochemistry, Molecular Biology +13

Comparative Metabolic Capabilities of CYP3A4, CYP3A5, and CYP3A7

J. Andrew Williams, Barbara J. Ring, Varon E. Cantrell et al. · Drug Metabolism and Disposition · 2002 · 468 citations

Medicine, Biochemistry, Pharmacology +17