Mary F. Paine

THE HUMAN INTESTINAL CYTOCHROME P450 “PIE”

Mary F. Paine, Heather L. Hart, Shana S. Ludington et al. · Drug Metabolism and Disposition · 2006 · 874 citations

Medicine, Biochemistry, Pharmacology +12

Characterization of Interintestinal and Intraintestinal Variations in Human CYP3A-Dependent Metabolism

Mary F. Paine, Mehraneh Khalighi, Jeannine M. Fisher et al. · Journal of Pharmacology and Experimental Therapeutics · 1997 · 792 citations

Medicine, Pharmacokinetics, Pharmacology +17

Oral first-pass elimination of midazolam involves both gastrointestinal and hepatic CYP3A-mediated metabolism*

Kenneth E. Thummel, Diarmuid O’Shea, Mary F. Paine et al. · Clinical Pharmacology & Therapeutics · 1996 · 619 citations

Pharmacy, Pharmacokinetics, Pharmacology +17

Expression of Enzymatically Active CYP3A4 by Caco-2 Cells Grown on Extracellular Matrix-Coated Permeable Supports in the Presence of 1α,25-Dihydroxyvitamin D3

Phyllissa Schmiedlin‐Ren, Kenneth E. Thummel, Jeannine M. Fisher et al. · Molecular Pharmacology · 1997 · 329 citations

Medicine, Pharmacology, Bioavailability +12

First-pass metabolism of midazolam by the human intestine*

Mary F. Paine, Danny D. Shen, Kent L. Kunze et al. · Clinical Pharmacology & Therapeutics · 1996 · 304 citations

Medicine, Pharmacokinetics, Pharmacology +16