Kent L. Kunze

Characterization of Interintestinal and Intraintestinal Variations in Human CYP3A-Dependent Metabolism

Mary F. Paine, Mehraneh Khalighi, Jeannine M. Fisher et al. · Journal of Pharmacology and Experimental Therapeutics · 1997 · 792 citations

Medicine, Pharmacokinetics, Pharmacology +17

Oral first-pass elimination of midazolam involves both gastrointestinal and hepatic CYP3A-mediated metabolism*

Kenneth E. Thummel, Diarmuid O’Shea, Mary F. Paine et al. · Clinical Pharmacology & Therapeutics · 1996 · 619 citations

Pharmacy, Pharmacokinetics, Pharmacology +17

Hydroxylation of warfarin by human cDNA-expressed cytochrome P-450: a role for P-4502C9 in the etiology of (S)-warfarin-drug interactions

Allan E. Rettie, Kenneth R. Korzekwa, Kent L. Kunze et al. · Chemical Research in Toxicology · 1992 · 602 citations

Medicine, Pharmacology, Toxicology +17

Use of midazolam as a human cytochrome P450 3A probe: I. In vitro-in vivo correlations in liver transplant patients.

Kenneth E. Thummel, Danny D. Shen, Terry Podoll et al. · Journal of Pharmacology and Experimental Therapeutics · 1994 · 356 citations

Pharmacy, Pharmacokinetics, Pharmacology +17

Interpatient heterogeneity in expression of CYP3A4 and CYP3A5 in small bowel: Lack of prediction by the erythromycin breath test

Paul B. Watkins, Steven Wrighton, Jeffrey L. Barnett et al. · Carolina Digital Repository (University of North Carolina at Chapel Hill) · 2019 · 305 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +12