Unanticipated retention of configuration in the DAST fluorination of deoxy-4′-thiopyrimidine nucleosides with “up” hydroxyl groups

Nucleoside syntheses, XXII¹⁾ Nucleoside synthesis with trimethylsilyl triflate and perchlorate as catalysts

Helmut Vorbrüggen, Konrad Krolikiewicz, Bärbel Bennua · Chemische Berichte · 1981 · 755 citations

Natural Sciences, Chemistry, Catalysis +14

Acid-stable 2'-fluoro purine dideoxynucleosides as active agents against HIV

Víctor E. Márquez, Christopher K. H. Tseng, Hiroaki Mitsuya et al. · Journal of Medicinal Chemistry · 1990 · 211 citations

Medicine, Medicinal Chemistry, Pharmacology +15

Anti-retrovirus activity of 3′-fluoro- and 3′-azido-substituted pyrimidine 2′,3′-dideoxynucleoside analogues

Jan Balzarini, Masanori Baba, Rudi Pauwels et al. · Biochemical Pharmacology · 1988 · 191 citations

Medicine, Medicinal Chemistry, Pharmacology +12

Synthesis and biological activity of 2'-deoxy-4'-thio pyrimidine nucleosides

John A. Secrist, Kamal N. Tiwari, James M. Riordan et al. · Journal of Medicinal Chemistry · 1991 · 177 citations

Life Sciences, Biochemistry, Chemistry +13

4-(1,2,4-Triazol-1-yl)- and 4-(3-nitro-1,2,4-triazol-1-yl)-1-(β-<scp>D</scp>-2,3,5-tri-O-acetylarabinofuranosyl)pyrimidin-2(1H)-ones. Valuable intermediates in the synthesis of derivatives of 1-(β-<scp>D</scp>-arabinofuranosyl)cytosine (ara-C)

K. J. DIVAKAR, Colin B. Reese · Journal of the Chemical Society Perkin Transactions 1 · 1982 · 163 citations

Natural Sciences, Chemistry, Medicinal Chemistry +8