Concepedia

Fluorination Effects

Fluorination Effects is a chemical modulation strategy within lipophilicity optimization that specifically describes the alteration of a molecule's lipophilic character through the introduction of fluorine atoms, distinguished by the unique electronic and steric properties of fluorine that influence hydrophobicity, metabolic stability, and membrane permeability.

1.3K

Publications

57.8K

Citations

5.3K

Authors

1.3K

Institutions

Publications per year

2017–2026

371

Parents

Publications

1.3K

Fluorine substituent effects (on bioactivity)

Bruce E. Smart · Journal of Fluorine Chemistry · 2001 · 1.5K citations

, , +4

Fluorine in medicinal chemistry: Recent therapeutic applications of fluorinated small molecules

Kenneth L. Kirk · Journal of Fluorine Chemistry · 2006 · 892 citations

, , +13

Effects of TiO<sub>2</sub> Surface Fluorination on Photocatalytic Reactions and Photoelectrochemical Behaviors

Hyunwoong Park, Wonyong Choi · The Journal of Physical Chemistry B · 2004 · 619 citations

, , +17

Recent advances (1995–2005) in fluorinated pharmaceuticals based on natural products

Journal of Fluorine Chemistry · 2006 · 587 citations

, , +7

Some influences of fluorine in bioorganic chemistry

David O’Hagan, Henry S. Rzepa · Chemical Communications · 1997 · 472 citations

, , +6

1–5 of 1.3K

Authors

5.3K

  1. BD
    Boxue Du

    Tianjin University, China

    15 publications · 541 citations

    14

    h-index

  2. LA
    Lucius A. Bigelow

    14 publications · 286 citations

    12

    h-index

  3. MD
    Marc Dubois

    Centre National de la Recherche Scientifique, France

    12 publications · 390 citations

    11

    h-index

  4. YL
    Young‐Seak Lee

    Chungnam National University, South Korea

    11 publications · 695 citations

    11

    h-index

  5. ZA
    Zhenlian An

    Tongji University, China

    11 publications · 326 citations

    11

    h-index

1–5 of 5.3K

Institutions

1.3K

  1. Centre National de la Recherche Scientifique

    Paris, France

    32 h-index

    306 publications

    12.1K citations

  2. Chinese Academy of Sciences

    Beijing, China

    26 h-index

    192 publications

    13K citations

  3. Sichuan University

    Chengdu, China

    19 h-index

    140 publications

    6.2K citations

  4. Tianjin University

    Tianjin, China

    18 h-index

    68 publications

    2.4K citations

  5. University of Chinese Academy of Sciences

    Beijing, China

    16 h-index

    72 publications

    3.2K citations

  6. Lawrence Berkeley National Laboratory

    Berkeley, United States

    15 h-index

    49 publications

    3.8K citations

  7. Tongji University

    Shanghai, China

    14 h-index

    79 publications

    2.7K citations

  8. Institute of Energy Problems of Chemical Physics

    Moscow, Russia

    13 h-index

    18 publications

    1.3K citations

1–8 of 1.3K

Venues

  1. Journal of Fluorine Chemistry

    102 publications · 6.5K citations

    35

    h-index

  2. Journal of the American Chemical Society

    JACS · 55 publications · 4.3K citations

    31

    h-index

  3. The Journal of Organic Chemistry

    JOC · 32 publications · 1.5K citations

    24

    h-index

  4. Angewandte Chemie International Edition

    21 publications · 1.3K citations

    20

    h-index

  5. Chemistry - A European Journal

    29 publications · 1.2K citations

    19

    h-index

1–5