Víctor E. Márquez

Somatic mutations at EZH2 Y641 act dominantly through a mechanism of selectively altered PRC2 catalytic activity, to increase H3K27 trimethylation

Damian Yap, Justin Chu, Tobias Berg et al. · Blood · 2010 · 597 citations · Full text

Life Sciences, Genetics, Molecular Biology +16

DZNep is a global histone methylation inhibitor that reactivates developmental genes not silenced by DNA methylation

Tina Branscombe Miranda, Connie C. Cortez, Christine B. Yoo et al. · Molecular Cancer Therapeutics · 2009 · 597 citations · Full text

Medicine, Oncology, Pharmacology +16

Inhibition of DNA Methylation and Reactivation of Silenced Genes by Zebularine

Jian‐Chun Cheng, Cindy Matsen, Felicidad A. Gonzales et al. · JNCI Journal of the National Cancer Institute · 2003 · 534 citations · Full text

Medicine, Oncology, Pharmacology +14

EZH2 Is Essential for Glioblastoma Cancer Stem Cell Maintenance

Mario-Luca Suvà, Nicolò Riggi, Michalina Janiszewska et al. · Cancer Research · 2009 · 470 citations · Full text

Medicine, Cancer Biology, Oncology +12

Cancer mediates effector T cell dysfunction by targeting microRNAs and EZH2 via glycolysis restriction

Ende Zhao, Tomasz Maj, Ilona Kryczek et al. · Nature Immunology · 2015 · 405 citations

Medicine, Molecular Biology, Oncology +14