Damian Yap

The clonal and mutational evolution spectrum of primary triple-negative breast cancers

Sohrab P. Shah, Andrew Roth, Rodrigo Goya et al. · Nature · 2012 · 2K citations

Breast Oncology, Tumor Heterogeneity, Medicine +10

Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin

Ryan D. Morin, Nathalie A. Johnson, Tesa Severson et al. · Nature Genetics · 2010 · 1.6K citations · Full text

Tumor Biology, Lymphoid Neoplasia, Large B-cell Lymphomas +9

PyClone: statistical inference of clonal population structure in cancer

Andrew Roth, Jaswinder Khattra, Damian Yap et al. · Nature Methods · 2014 · 1K citations · Full text

Oncology, Tumor Heterogeneity, Medicine +6

Dynamics of genomic clones in breast cancer patient xenografts at single-cell resolution

Peter Eirew, Adi Steif, Jaswinder Khattra et al. · Nature · 2014 · 630 citations · Full text

Xenotransplantation, Somatic Variant, Tumor Heterogeneity +12

Somatic mutations at EZH2 Y641 act dominantly through a mechanism of selectively altered PRC2 catalytic activity, to increase H3K27 trimethylation

Damian Yap, Justin Chu, Tobias Berg et al. · Blood · 2010 · 592 citations · Full text