The Genome Sequence of the SARS-Associated Coronavirus

Marco A. Marra, Steven J.M. Jones, Caroline R. Astell, +56

Science

The clonal and mutational evolution spectrum of primary triple-negative breast cancers

Sohrab P. Shah, Andrew Roth, Rodrigo Goya, +56

Nature

Breast OncologyTumor HeterogeneityMedicinePathologyCancer Genomics +8

Mutational evolution in a lobular breast tumour profiled at single nucleotide resolution

Sohrab P. Shah, Ryan D. Morin, Jaswinder Khattra, +26

Nature

PyClone: statistical inference of clonal population structure in cancer

Andrew Roth, Jaswinder Khattra, Damian Yap, +7

Nature Methods

OncologyTumor HeterogeneityMedicineClonal Population StructureCancer Genomics +4

Mutation of <i>FOXL2</i> in Granulosa-Cell Tumors of the Ovary

Sohrab P. Shah, Martin Köbel, Janine Senz, +38

New England Journal of Medicine

Dynamics of genomic clones in breast cancer patient xenografts at single-cell resolution

Peter Eirew, Adi Steif, Jaswinder Khattra, +43

Nature

XenotransplantationSomatic VariantTumor HeterogeneitySingle-cell ResolutionMedicine +10

TITAN: inference of copy number architectures in clonal cell populations from tumor whole-genome sequence data

Gavin Ha, Andrew Roth, Jaswinder Khattra, +18

Genome Research

Clonal Cell PopulationsEngineeringCopy Number ArchitecturesGeneticsGenomics +17

Divergent modes of clonal spread and intraperitoneal mixing in high-grade serous ovarian cancer

Andrew McPherson, Andrew Roth, Emma Laks, +31

Nature Genetics

Surgical OncologyTumoral PathologyMedicineClonal SpreadDivergent Modes +7

Functional Genomics of the Cilium, a Sensory Organelle

Oliver E. Blacque, Elliot A. Perens, Keith A. Boroevich, +16

Current Biology

BiologySensory OrganelleCell OrganelleIntercellular CommunicationMolecular Genetics +3

Analysis of long-lived <i>C. elegans daf-2</i> mutants using serial analysis of gene expression

Julius Halaschek-Wiener, Jaswinder Khattra, Sheldon McKay, +8

Genome Research

AgingFamily MembersGeneticsMolecular GeneticsGene Regulatory Network +14