Anti-retrovirus activity of 3′-fluoro- and 3′-azido-substituted pyrimidine 2′,3′-dideoxynucleoside analogues

Detection, Isolation, and Continuous Production of Cytopathic Retroviruses (HTLV-III) from Patients with AIDS and Pre-AIDS

Mikuláš Popovič, M. G. Sarngadharan, Elizabeth J. Read et al. · Science · 1984 · 3.5K citations

Life Sciences, Immunology, Molecular Biology +17

3'-Azido-3'-deoxythymidine (BW A509U): an antiviral agent that inhibits the infectivity and cytopathic effect of human T-lymphotropic virus type III/lymphadenopathy-associated virus in vitro.

Hiroaki Mitsuya, Kent J. Weinhold, P A Furman et al. · Proceedings of the National Academy of Sciences · 1985 · 1.9K citations · Full text

Life Sciences, Infectious Diseases, Molecular Biology +17

Nucleosides. V. The Monomesylates of 1-(2'-Deoxy-β-D-lyxofuranosyl)thymine^1,2

Jerome P. Horwitz, Jonathan Chua, Michael Noel · The Journal of Organic Chemistry · 1964 · 348 citations

Natural Sciences, Chemistry, Bioorthogonal Chemistry +8

Both 2′,3′-dideoxythymidine and its 2′,3′-unsaturated derivative (2′,3′-dideoxythymidinene) are potent and selective inhibitors of human immunodeficiency virus replication in vitro

Masanori Baba, Rudi Pauwels, Piet Herdewijn et al. · Biochemical and Biophysical Research Communications · 1987 · 344 citations

Life Sciences, Medicinal Chemistry, Molecular Biology +13

3'-Substituted 2',3'-dideoxynucleoside analogs as potential anti-HIV (HTLV-III/LAV) agents

Piet Herdewijn, Jan Balzarini, Erik De Clercq et al. · Journal of Medicinal Chemistry · 1987 · 296 citations

Medicine, Medicinal Chemistry, Pharmacology +15