Lak Shin Jeong

Decreased expression of synapse-related genes and loss of synapses in major depressive disorder

Hyo Jung Kang, Bhavya Voleti, Tibor Hajszán et al. · Nature Medicine · 2012 · 815 citations · Full text

Life Sciences, Neurobiology, Neuroscience +14

Activities of the four optical isomers of 2',3'-dideoxy-3'-thiacytidine (BCH-189) against human immunodeficiency virus type 1 in human lymphocytes

Raymond F. Schinazi, C. K. CHU, A Peck et al. · Antimicrobial Agents and Chemotherapy · 1992 · 265 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +9

The Nedd8-Activating Enzyme Inhibitor MLN4924 Induces Autophagy and Apoptosis to Suppress Liver Cancer Cell Growth

Zhongguang Luo, Guangyang Yu, Hyuk Woo Lee et al. · Cancer Research · 2012 · 241 citations · Full text

Life Sciences, Oncology, Pharmacology +17

Deoxycytidine deaminase-resistant stereoisomer is the active form of (+/-)-2',3'-dideoxy-3'-thiacytidine in the inhibition of hepatitis B virus replication.

C.N. Chang, Shin-Lian Doong, Junhu Zhou et al. · Journal of Biological Chemistry · 1992 · 225 citations · Full text

Life Sciences, Infectious Diseases, Pharmacology +13

Synthesis of enantiomerically pure (2'R,5'S)-(-)-1-(2-hydroxymethyloxathiolan-5-yl)cytosine as a potent antiviral agent against hepatitis B virus (HBV) and human immunodeficiency virus (HIV)

Joseph Warren Beach, Lak Shin Jeong, Antônio J. Alves et al. · The Journal of Organic Chemistry · 1992 · 192 citations

Medicine, Medicinal Chemistry, Pharmacology +6