Concepedia

Development of an oxazolopyridine series of dual thrombin/factor Xa inhibitors via structure-guided lead optimization

James Z. Deng, Daniel R. McMasters, Philippe M. A. Rabbat, Peter Williams, Craig A. Coburn, Youwei Yan, Lawrence C. Kuo, Sidney D. Lewis, Bobby J. Lucas, Julie A. Krueger,

Bioorganic & Medicinal Chemistry Letters · 2005 · 41 citations · 12 references

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12

An introduction to hydrogen bonding

Choice Reviews Online · 1998 · 6.3K citations

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The Hydrogen Bond in the Solid State

Thomas Steiner · Angewandte Chemie International Edition · 2002 · 6.2K citations

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Rat model of arterial thrombosis induced by ferric chloride

K D Kurz, Bradley W. Main, George E. Sandusky · Thrombosis Research · 1990 · 427 citations

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Conformational Selection of Inhibitors and Substrates by Proteolytic Enzymes:  Implications for Drug Design and Polypeptide Processing

David P. Fairlie, Joel D. A. Tyndall, Robert C. Reid et al. · Journal of Medicinal Chemistry · 2000 · 152 citations · Full text

, , +17

Metabolism-Directed Optimization of 3-Aminopyrazinone Acetamide Thrombin Inhibitors. Development of an Orally Bioavailable Series Containing P1 and P3 Pyridines

Christopher S. Burgey, Kyle A. Robinson, Terry A. Lyle et al. · Journal of Medicinal Chemistry · 2003 · 121 citations · Full text

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