Sidney D. Lewis

Reactivity of small thiolate anions and cysteine-25 in papain toward methyl methanethiosulfonate

David D. Roberts, Sidney D. Lewis, David P. Ballou et al. · Biochemistry · 1986 · 200 citations

Life Sciences, Biochemistry, Chemistry +8

Effect of cysteine-25 on the ionization of histidine-159 in papain as determined by proton nuclear magnetic resonance spectroscopy. Evidence for a histidine-159-cysteine-25 ion pair and its possible role in catalysis

Sidney D. Lewis, Fred A. Johnson, Jules A. Shafer · Biochemistry · 1981 · 155 citations

Life Sciences, Biochemistry, Chemistry +10

Steady state kinetic parameters for the thrombin-catalyzed conversion of human fibrinogen to fibrin.

Deborah L. Higgins, Sidney D. Lewis, Jules A. Shafer · Journal of Biological Chemistry · 1983 · 153 citations · Full text

Life Sciences, Biochemistry, Enzyme Mechanism +9

Potentiometric determination of ionizations at the active site of papain

Sidney D. Lewis, Fred A. Johnson, Jules A. Shafer · Biochemistry · 1976 · 128 citations

Natural Sciences, Biochemistry, Chemistry +12

Metabolism-Directed Optimization of 3-Aminopyrazinone Acetamide Thrombin Inhibitors. Development of an Orally Bioavailable Series Containing P1 and P3 Pyridines

Christopher S. Burgey, Kyle A. Robinson, Terry A. Lyle et al. · Journal of Medicinal Chemistry · 2003 · 121 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +17