Concepedia

A small molecule AMPK activator protects the heart against ischemia–reperfusion injury

Agnes S. Kim, Edward J. Miller, Tracy M. Wright, Ji Li, Dake Qi, Kwame Atsina, Vlad G. Zaha, Kei Sakamoto, Lawrence H. Young

Journal of Molecular and Cellular Cardiology · 2011 · 168 citations · 40 references

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References

40

Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium.

Charles E. Murry, Robert B. Jennings, K A Reimer · Circulation · 1986 · 7.8K citations · Full text

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Evidence that metformin exerts its anti-diabetic effects through inhibition of complex 1 of the mitochondrial respiratory chain

Mark R. Owen, E. Doran, Andrew P. Halestrap · Biochemical Journal · 2000 · 2.1K citations · Full text

, , +17

Distinct Roles of Autophagy in the Heart During Ischemia and Reperfusion

Yutaka Matsui, Hiromitsu Takagi, Xueping Qu et al. · Circulation Research · 2007 · 1.5K citations

, , +14

Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state

Marc Foretz, Sophie Hébrard, Jocelyne Leclerc et al. · Journal of Clinical Investigation · 2010 · 1.2K citations · Full text

, , +17

Adiponectin protects against myocardial ischemia-reperfusion injury through AMPK- and COX-2–dependent mechanisms

Rei Shibata, Kaori Sato, David R. Pimentel et al. · Nature Medicine · 2005 · 977 citations · Full text

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