Kei Sakamoto

Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state

Marc Foretz, Sophie Hébrard, Jocelyne Leclerc et al. · Journal of Clinical Investigation · 2010 · 1.2K citations · Full text

Lkb1/ampk Pathway, Insulin Signaling, Metabolic Syndrome +25

The Ancient Drug Salicylate Directly Activates AMP-Activated Protein Kinase

Simon A. Hawley, Morgan D. Fullerton, Fiona A. Ross et al. · Science · 2012 · 723 citations

Signal Transduction, Oxysterol, Biochemistry +14

Anti-Inflammatory Effects of Metformin Irrespective of Diabetes Status

Amy Cameron, Vicky L. Morrison, Daniel L. Levin et al. · Circulation Research · 2016 · 686 citations · Full text

Role that phosphorylation of GSK3 plays in insulin and Wnt signalling defined by knockin analysis

Edward J. McManus, Kei Sakamoto, Laura J Armit et al. · The EMBO Journal · 2005 · 594 citations · Full text

Signal Transduction, Gsk3 Plays, Signaling Pathway +10

Deficiency of LKB1 in skeletal muscle prevents AMPK activation and glucose uptake during contraction

Kei Sakamoto, Afshan McCarthy, Darrin P. Smith et al. · The EMBO Journal · 2005 · 544 citations · Full text

Muscle Function, Signal Transduction, Molecular Physiology +8