Afshan McCarthy

BRCA1 Basal-like Breast Cancers Originate from Luminal Epithelial Progenitors and Not from Basal Stem Cells

Gemma Molyneux, Felipe C. Geyer, Fiona‐Ann Magnay et al. · Cell stem cell · 2010 · 808 citations · Full text

Medicine, Cancer Biology, Oncology +16

Synthetic lethal targeting of PTEN mutant cells with PARP inhibitors

Ana M. Mendes‐Pereira, Sarah A. Martin, Rachel Brough et al. · EMBO Molecular Medicine · 2009 · 633 citations · Full text

Life Sciences, Molecular Biology, Oncology +14

Deficiency of LKB1 in skeletal muscle prevents AMPK activation and glucose uptake during contraction

Kei Sakamoto, Afshan McCarthy, Darrin P. Smith et al. · The EMBO Journal · 2005 · 547 citations · Full text

Life Sciences, Biochemistry, Cell Biology +10

Genome editing reveals a role for OCT4 in human embryogenesis

Norah M. E. Fogarty, Afshan McCarthy, Kirsten E Snijders et al. · Nature · 2017 · 396 citations · Full text

Life Sciences, Developmental Biology, Genetics +14

A Marker of Homologous Recombination Predicts Pathologic Complete Response to Neoadjuvant Chemotherapy in Primary Breast Cancer

Monika Graeser, Afshan McCarthy, Christopher J. Lord et al. · Clinical Cancer Research · 2010 · 326 citations · Full text

Medicine, Cancer Biology, Oncology +12