Sarah A. Martin

Synthetic lethal targeting of PTEN mutant cells with PARP inhibitors

Ana M. Mendes‐Pereira, Sarah A. Martin, Rachel Brough et al. · EMBO Molecular Medicine · 2009 · 633 citations · Full text

Life Sciences, Molecular Biology, Oncology +14

DNA Polymerases as Potential Therapeutic Targets for Cancers Deficient in the DNA Mismatch Repair Proteins MSH2 or MLH1

Sarah A. Martin, Nuala McCabe, Michelle J Mullarkey et al. · Cancer Cell · 2010 · 203 citations · Full text

Life Sciences, Genetics, Oncology +17

Methotrexate induces oxidative DNA damage and is selectively lethal to tumour cells with defects in the DNA mismatch repair gene MSH2

Sarah A. Martin, Afshan McCarthy, Louise J. Barber et al. · EMBO Molecular Medicine · 2009 · 158 citations · Full text

Medicine, Genetics, Oncology +17

Reduced Expression of Histone Methyltransferases KMT2C and KMT2D Correlates with Improved Outcome in Pancreatic Ductal Adenocarcinoma

Joshua B.N. Dawkins, Jun Wang, Eleni Maniati et al. · Cancer Research · 2016 · 111 citations · Full text

Medicine, Molecular Biology, Oncology +16

Hepatic TM6SF2 Is Required for Lipidation of VLDL in a Pre-Golgi Compartment in Mice and Rats

Fei Luo, Ēriks Šmagris, Sarah A. Martin et al. · Cellular and Molecular Gastroenterology and Hepatology · 2021 · 109 citations · Full text

Life Sciences, Biochemistry, Cellular Biochemistry +16