Christopher J. Lord

Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy

Hannah Farmer, Nuala McCabe, Christopher J. Lord et al. · Nature · 2005 · 6.7K citations

Life Sciences, Genetics, Molecular Biology +16

DNA-Repair Defects and Olaparib in Metastatic Prostate Cancer

Joaquı́n Mateo, Suzanne Carreira, Shahneen Sandhu et al. · New England Journal of Medicine · 2015 · 2.2K citations · Full text

Medicine, Molecular Biology, Oncology +17

Deficiency in the Repair of DNA Damage by Homologous Recombination and Sensitivity to Poly(ADP-Ribose) Polymerase Inhibition

Nuala McCabe, Nicholas C. Turner, Christopher J. Lord et al. · Cancer Research · 2006 · 1.3K citations

Life Sciences, Molecular Biology, Oncology +17

Resistance to therapy caused by intragenic deletion in BRCA2

Stacey L. Edwards, Rachel Brough, Christopher J. Lord et al. · Nature · 2008 · 1K citations

Medicine, Genetics, Molecular Genetics +11

Early Adaptation and Acquired Resistance to CDK4/6 Inhibition in Estrogen Receptor–Positive Breast Cancer

María Teresa Herrera-Abreu, Marta Palafox, Uzma Asghar et al. · Cancer Research · 2016 · 779 citations · Full text

Medicine, Cancer Biology, Oncology +17