Cardiac macrophage migration inhibitory factor inhibits JNK pathway activation and injury during ischemia/reperfusion

Dake Qi, Xiaoyue Hu, Xiaohong Wu, +4

Journal of Clinical Investigation

Cardiac MuscleImmunologyCell DeathActivated JnkCardiovascular Function +18

A small molecule AMPK activator protects the heart against ischemia–reperfusion injury

Agnes S. Kim, Edward J. Miller, Tracy M. Wright, +6

Journal of Molecular and Cellular Cardiology

Molecular PhysiologyCardiovascular DiseaseIschemia–reperfusion InjuryMedicinePhysiology +6

Cardiomyocyte apoptosis induced by short-term diabetes requires mitochondrial GSH depletion

Sanjoy Ghosh, Thomas Pulinilkunnil, Gloria Yuen, +5

American Journal of Physiology-Heart and Circulatory Physiology

Stz AdministrationHeart FailureLipid PeroxidationApoptosisCell Death +17

Single-Dose Dexamethasone Induces Whole-Body Insulin Resistance and Alters Both Cardiac Fatty Acid and Carbohydrate Metabolism

Dake Qi, Thomas Pulinilkunnil, An Ding, +7

Diabetes

Cardiac GlycolysisInsulin SignalingMetabolic SyndromeDex HeartsMetabolic Signaling +15

The metabolic “switch” AMPK regulates cardiac heparin-releasable lipoprotein lipase

An Ding, Thomas Pulinilkunnil, Dake Qi, +3

American Journal of Physiology-Endocrinology and Metabolism

Metabolic SyndromeBiochemistryCardiovascular DiseaseFatty AcidsMedicine +11

TLR4 regulates cardiac lipid accumulation and diabetic heart disease in the nonobese diabetic mouse model of type 1 diabetes

Baojun Dong, Dake Qi, Long Yang, +5

American Journal of Physiology-Heart and Circulatory Physiology

Diabetic Heart DiseaseImmunologyToll-like ReceptorP38 MapkTlr4 Deficiency +19

The vestigial enzyme D-dopachrome tautomerase protects the heart against ischemic injury

Dake Qi, Kwame Atsina, Lintao Qu, +9

Journal of Clinical Investigation

Cardiac MuscleHeart FailureImmunologyCell DeathCellular Physiology +17

AMPK is critical for mitochondrial function during reperfusion after myocardial ischemia

Vlad G. Zaha, Dake Qi, Kevin N Su, +8

Journal of Molecular and Cellular Cardiology

Myocardial IschemiaCardiac MuscleMolecular PhysiologyCardiovascular DiseaseMitochondrial Function +8

Venlafaxine inhibits the upregulation of plasma tumor necrosis factor-alpha (TNF-α) in the Chinese patients with major depressive disorder: A prospective longitudinal study

Zezhi Li, Dake Qi, Jun Chen, +8

Psychoneuroendocrinology

InflammationClinical DisordersProspective Longitudinal StudyPsychoneuroimmunologyPsychiatric Disease +10

AMPK control of myocardial fatty acid metabolism fluctuates with the intensity of insulin-deficient diabetes

Girish Kewalramani, An Ding, Min Suk Kim, +9

Journal of Molecular and Cellular Cardiology

Metabolic SyndromeInsulin-deficient DiabetesHeart FailureInsulin SignalingCardiovascular Disease +12