Andrew P. Halestrap

Evidence that metformin exerts its anti-diabetic effects through inhibition of complex 1 of the mitochondrial respiratory chain

Mark R. Owen, E. Doran, Andrew P. Halestrap · Biochemical Journal · 2000 · 2.1K citations · Full text

Life Sciences, Biochemistry, Pharmacology +17

The proton-linked monocarboxylate transporter (MCT) family: structure, function and regulation

Andrew P. Halestrap, Nigel T. Price · Biochemical Journal · 1999 · 1.3K citations · Full text

Life Sciences, Biochemistry, Cell Biology +11

The Plasma Membrane Lactate Transporter MCT4, but Not MCT1, Is Up-regulated by Hypoxia through a HIF-1α-dependent Mechanism

Mohammed S. Ullah, Andrew Davies, Andrew P. Halestrap · Journal of Biological Chemistry · 2006 · 868 citations · Full text

Life Sciences, Molecular Biology, Physiology +17

Inhibition of Ca2+-induced large-amplitude swelling of liver and heart mitochondria by cyclosporin is probably caused by the inhibitor binding to mitochondrial-matrix peptidyl-prolyl <i>cis-trans</i> isomerase and preventing it interacting with the adenine nucleotide translocase

Andrew P. Halestrap, A M Davidson · Biochemical Journal · 1990 · 746 citations · Full text

Life Sciences, Biochemistry, Pharmacology +17

Identification of Monocarboxylate Transporter 8 as a Specific Thyroid Hormone Transporter

Edith C. H. Friesema, Sumita Ganguly, A. E. D. Abdalla et al. · Journal of Biological Chemistry · 2003 · 716 citations · Full text

Life Sciences, Biochemistry, Endocrinology +12