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Non-steroidal glucocorticoid agonists—The discovery of aryl pyrazoles as A-ring mimetics

Margaret Clackers, Diane M. Coe, Derek A. Demaine, George W. Hardy, Davina Humphreys, Graham G. A. Inglis, Michael J. Johnston, Haydn T. Jones, David House, Richard Loiseau,

Bioorganic & Medicinal Chemistry Letters · 2007 · 30 citations · 11 references

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11

Goodman and Gilman's the Pharmacological Basis of Therapeutics

William H. Stigelman, D Pharm · Military Medicine · 1986 · 6.8K citations

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Dissociation of transactivation from transrepression by a selective glucocorticoid receptor agonist leads to separation of therapeutic effects from side effects

Heike Schäcke, Arndt Schottelius, Wolf‐Dietrich Döcke et al. · Proceedings of the National Academy of Sciences · 2003 · 470 citations · Full text

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Design and evaluation of novel nonsteroidal dissociating glucocorticoid receptor ligands

Nilesh Shah, Thomas S. Scanlan · Bioorganic & Medicinal Chemistry Letters · 2004 · 80 citations · Full text

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Dissociated Nonsteroidal Glucocorticoid Receptor Modulators; Discovery of the Agonist Trigger in a Tetrahydronaphthalene−Benzoxazine Series

Mike D. Barker, Margaret Clackers, Royston C. B. Copley et al. · Journal of Medicinal Chemistry · 2006 · 77 citations · Full text

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Differentiation of in vitro transcriptional repression and activation profiles of selective glucocorticoid modulators

Steven W. Elmore, John K. Pratt, Michael J. Coghlan et al. · Bioorganic & Medicinal Chemistry Letters · 2004 · 57 citations · Full text

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