Derek A. Demaine

Dimeric Zanamivir Conjugates with Various Linking Groups Are Potent, Long-Lasting Inhibitors of Influenza Neuraminidase Including H5N1 Avian Influenza

Simon J. F. Macdonald, Rachel Cameron, Derek A. Demaine et al. · Journal of Medicinal Chemistry · 2005 · 87 citations · Full text

Medicinal Chemistry, Medicine, Plaque Reduction Assays +14

Potent and Long-Acting Dimeric Inhibitors of Influenza Virus Neuraminidase Are Effective at a Once-Weekly Dosing Regimen

Simon J. F. Macdonald, Keith G. Watson, Rachel Cameron et al. · Antimicrobial Agents and Chemotherapy · 2004 · 80 citations · Full text

Medicinal Chemistry, Antiviral Compound, Medicine +12

Dissociated Nonsteroidal Glucocorticoid Receptor Modulators; Discovery of the Agonist Trigger in a Tetrahydronaphthalene−Benzoxazine Series

Mike D. Barker, Margaret Clackers, Royston C. B. Copley et al. · Journal of Medicinal Chemistry · 2006 · 77 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Tetrahydronaphthalene-benzoxazine Glucocorticoid Receptor +15

Design and Synthesis of New Nonsteroidal Glucocorticoid Modulators through Application of an “Agreement Docking” Method

Mike D. Barker, Margaret Clackers, Derek A. Demaine et al. · Journal of Medicinal Chemistry · 2005 · 44 citations · Full text

Molecular Docking, Medicinal Chemistry, G Protein-coupled Receptor +10

Nonsteroidal Glucocorticoid Agonists: Tetrahydronaphthalenes with Alternative Steroidal A-Ring Mimetics Possessing Dissociated (Transrepression/Transactivation) Efficacy Selectivity

Keith Biggadike, Mohamed Boudjelal, Margaret Clackers et al. · Journal of Medicinal Chemistry · 2007 · 40 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Mmtv Agonism +14