Keith G. Watson

Structure-guided design of a selective BCL-XL inhibitor

Guillaume Lessène, Peter E. Czabotar, Brad E. Sleebs et al. · Nature Chemical Biology · 2013 · 370 citations · Full text

Drug Target, Medicine, Rational Drug Design +4

Discovery of a Potent and Selective BCL-X _L Inhibitor with <i>in Vivo</i> Activity

Zhi‐Fu Tao, Lisa Hasvold, Le Wang et al. · ACS Medicinal Chemistry Letters · 2014 · 328 citations · Full text

Dimeric Zanamivir Conjugates with Various Linking Groups Are Potent, Long-Lasting Inhibitors of Influenza Neuraminidase Including H5N1 Avian Influenza

Simon J. F. Macdonald, Rachel Cameron, Derek A. Demaine et al. · Journal of Medicinal Chemistry · 2005 · 87 citations · Full text

Medicinal Chemistry, Medicine, Plaque Reduction Assays +14

Stereoselective syntheses of ephedrine and related 2-aminoalcohols of high optical purity from protected cyanohydrins

W. R. JACKSON, Howard A. Jacobs, Barry Matthews et al. · Tetrahedron Letters · 1990 · 85 citations

Bioorganic Chemistry, Biochemistry, Natural Sciences +10

Potent and Long-Acting Dimeric Inhibitors of Influenza Virus Neuraminidase Are Effective at a Once-Weekly Dosing Regimen

Simon J. F. Macdonald, Keith G. Watson, Rachel Cameron et al. · Antimicrobial Agents and Chemotherapy · 2004 · 80 citations · Full text

Medicinal Chemistry, Antiviral Compound, Medicine +12