Concepedia

Guillaume Lessène

GL

Statistics

Publications

77

Citations

9.1K

H-Index

40

Active since

1999

Affiliations

Walter and Eliza Hall Institute of Medical Research(Current)

The University of Melbourne

Monash University

The Royal Melbourne Hospital

La Trobe University

Guillaume Lessène is an author at Walter and Eliza Hall Institute of Medical Research specializing in medicine, cell biology, and immunology.

Top concepts

MedicineCell BiologyImmunologyTumor BiologyCell DeathCell SignalingApoptosisPharmacologyCancer BiologyCancer Research

Publications per year

1999–2025

77

Publications

77

The MCL1 inhibitor S63845 is tolerable and effective in diverse cancer models

András Kotschy, Zoltán Szlávik, James B. Murray et al. · Nature · 2016 · 1K citations

Mcl1 Inhibitor S63845, Systems Biology, Oncology +11

BAK/BAX macropores facilitate mitochondrial herniation and mtDNA efflux during apoptosis

Kate McArthur, Lachlan Whitehead, John M. Heddleston et al. · Science · 2018 · 952 citations

Mitophagy, Apoptosis, Immunology +18

Apoptotic Caspases Suppress mtDNA-Induced STING-Mediated Type I IFN Production

M. J. D. White, Kate McArthur, Donald Metcalf et al. · Cell · 2014 · 918 citations · Full text

Mitochondrial Function, Apoptosis, Immunology +4

Activation of the pseudokinase MLKL unleashes the four-helix bundle domain to induce membrane localization and necroptotic cell death

Joanne M. Hildebrand, Maria C. Tanzer, Isabelle S. Lucet et al. · Proceedings of the National Academy of Sciences · 2014 · 581 citations · Full text

Mechanism and inhibition of the papain‐like protease, PLpro, of SARS‐CoV‐2

Theresa Klemm, Gregor Ebert, Dale J. Calleja et al. · The EMBO Journal · 2020 · 478 citations · Full text

Protein Function, Biochemistry, Natural Sciences +3

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