James B. Murray

The MCL1 inhibitor S63845 is tolerable and effective in diverse cancer models

András Kotschy, Zoltán Szlávik, James B. Murray et al. · Nature · 2016 · 1K citations

Mcl1 Inhibitor S63845, Systems Biology, Oncology +11

Capturing the Structure of a Catalytic RNA Intermediate: The Hammerhead Ribozyme

W. G. Scott, James B. Murray, John R. P. Arnold et al. · Science · 1996 · 409 citations

Crystal Structure, Active Rna Fold, Biochemistry +12

Crystal structure of an RNA bacteriophage coat protein–operator complex

K. Valegård, James B. Murray, Peter G. Stockley et al. · Nature · 1994 · 375 citations

Crystal Structure, Bacteriophage, Protein X-ray Crystallography +2

The hammerhead, hairpin and VS ribozymes are catalytically proficient in monovalent cations alone

James B. Murray, Attila A. Seyhan, Nils G. Walter et al. · Chemistry & Biology · 1998 · 372 citations · Full text

Biochemistry, Natural Sciences, Enzyme Catalysis +8

A novel, small molecule inhibitor of Hsc70/Hsp70 potentiates Hsp90 inhibitor induced apoptosis in HCT116 colon carcinoma cells

Andrew J. Massey, D.S. Williamson, Helen Browne et al. · Cancer Chemotherapy and Pharmacology · 2009 · 327 citations · Full text

Medicine, Apoptosis, Cell Death +7