Concepedia

A novel, small molecule inhibitor of Hsc70/Hsp70 potentiates Hsp90 inhibitor induced apoptosis in HCT116 colon carcinoma cells

Andrew J. Massey, D.S. Williamson, Helen Browne, James B. Murray, P. Dokurno, T. Shaw, Alba T. Macias, Zoe Daniels, Stephanie Geoffroy, Melanie Dopson,

Cancer Chemotherapy and Pharmacology · 2009 · 329 citations · 33 references

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33

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

Christopher A. Lipinski, Franco Lombardo, Beryl W. Dominy et al. · Advanced Drug Delivery Reviews · 1997 · 11.2K citations

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Molecular Properties That Influence the Oral Bioavailability of Drug Candidates

Daniel F. Veber, Stephen R. Johnson, Hung‐Yuan Cheng et al. · Journal of Medicinal Chemistry · 2002 · 8.1K citations

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Identifying and Characterizing Binding Sites and Assessing Druggability

Thomas A. Halgren · Journal of Chemical Information and Modeling · 2009 · 1.8K citations

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Molecular chaperones and the stress of oncogenesis

Dick D. Mosser, Richard I. Morimoto · Oncogene · 2004 · 502 citations

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Phase I Pharmacokinetic and Pharmacodynamic Study of 17-Allylamino, 17-Demethoxygeldanamycin in Patients With Advanced Malignancies

Udai Banerji, Anne O’Donnell, Michelle Scurr et al. · Journal of Clinical Oncology · 2005 · 491 citations · Full text

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