Le Wang

Genome sequence of the progenitor of the wheat D genome Aegilops tauschii

Ming‐Cheng Luo, Yong Gu, Daniela Puiu et al. · Nature · 2017 · 693 citations · Full text

Exploiting selective BCL-2 family inhibitors to dissect cell survival dependencies and define improved strategies for cancer therapy

Darren C. Phillips, Michael J. Mitten, Erwin R. Boghaert et al. · Science Translational Medicine · 2015 · 530 citations · Full text

Cancer Therapy, Chemoprevention Strategy, Bcl-2/bcl-xl/bcl-w Inhibitor Abt-263 +20

Discovery of a Potent and Selective BCL-X _L Inhibitor with <i>in Vivo</i> Activity

Zhi‐Fu Tao, Lisa Hasvold, Le Wang et al. · ACS Medicinal Chemistry Letters · 2014 · 328 citations · Full text

Structure-Guided Design of a Series of MCL-1 Inhibitors with High Affinity and Selectivity

Milan Bruncko, Le Wang, George S. Sheppard et al. · Journal of Medicinal Chemistry · 2015 · 150 citations · Full text

Drug Target, Mcl-1 Inhibitors, High Throughput +23

Type-I-interferon signaling drives microglial dysfunction and senescence in human iPSC models of Down syndrome and Alzheimer’s disease

Mengmeng Jin, Ranjie Xu, Le Wang et al. · Cell stem cell · 2022 · 149 citations · Full text

Down Syndrome, Human Ipsc Models, Neurodegenerative Diseases +12